CAS RN: 1002304-34-8
AMG-208
Product Availability
Choose a grade to view its available package options.
8 package records2 with current stock2 grade groups
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20250524 | 100mg | Out of stock | Inquiry | |
| Batchno.20250226 | 10mg | Out of stock | Inquiry | |
| Batchno.20250704 | 1mg | Out of stock | Inquiry | |
| Batchno.20251023 | 25mg | Out of stock | Inquiry | |
| Batchno.20250914 | 50mg | Out of stock | Inquiry | |
| Batchno.20260618 | 5mg | Out of stock | Inquiry |
- Product code: starshine_CAS1002304-34-8
- Purity/Analytical Methods: >99.0%
1002304-34-8 / 7-methoxy-4-[(6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy]quinoline
AMG-208 | AMG 208 | AMG208
Basic Information
CAS
1002304-34-8
Multi CAS
No
Molecular Formula
C22H17N5O2
Molecular Weight
383.400000
Exact Mass
383.138225
SMILES
COC1=CC2=NC=CC(=C2C=C1)OCC3=NN=C4N3N=C(C=C4)C5=CC=CC=C5
InChI
InChI=1S/C22H17N5O2/c1-28-16-7-8-17-19(13-16)23-12-11-20(17)29-14-22-25-24-21-10-9-18(26-27(21)22)15-5-3-2-4-6-15/h2-13H,14H2,1H3
InChIKey
HEAIZQNMNCHNFD-UHFFFAOYSA-N
Synonyms
AMG-208
AMG 208
AMG208
7-methoxy-4-((6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy)quinoline
Y2SR66P7VM
Computed Properties
Structural Parameters
Heavy atom count
29
Aromatic heavy atom count
25
Fraction Csp3
0.09
Rotatable bonds
5
H-bond acceptors
7
Molar refractivity
108.84
TPSA
74.43
LogP / Solubility
WLOGP
3.93
MLOGP
3.48
XLogP3
3.1
Consensus LogP
3.5
Log S (ESOL)
-5
Class (ESOL)
Slightly soluble
Log S (Ali)
-5.54
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-6.01
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
No
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-2.27
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
3.5
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![CAS 1002309-47-8 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]thiazole molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1002309-47-8.gif)
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